In order to understand Barrett’s esophagus, it is useful to understand the normal appearance of the esophagus. In the normal esophagus, the tissue lining appears pale pink and smooth. These flat square cells, called “squamous” (Latin for square) cells, make up the normal lining of the esophagus.
In contrast, Barrett’s esophagus is a salmon-colored lining in the esophagus (see Cartoon 3), made up of cells that are similar to cells found in the small intestine and are called “specialized intestinal metaplasia.”
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